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. 2014 Nov 21;3:11–17. doi: 10.1016/j.bbacli.2014.11.004

Table 4.

Association between molecular marker expressions and clinicopathological features in OSCC patients (n = 97).

Clinicopathological features Cyclin-D1
EGFR
p53
Negative (n = 13) (%) Moderate positive (n = 64) (%) Strong positive (n = 20) (%) p value Negative (n = 7) (%) Moderate positive (n = 59) (%) Strong positive (n = 31) (%) p value Negative (n = 14) (%) Moderate positive (n = 62) (%) Strong positive (n = 21) (%) p value
Grade
 MD/PD 5 (38.5) 20 (31.3) 7 (35.0) 0.861 3 (42.9) 19 (32.2) 10 (32.3) 0.847 6 (42.9) 22 (35.5) 4 (19.0) 0.267
 WD 8 (61.5) 44 (68.8) 13 (65.0) 4 (57.1) 40 (67.8) 21 (67.7) 8 (57.1) 40 (64.5) 17 (81.0)
Tumor size
 T2/T3 4 (30.8) 16 (25.0) 4 (20.0) 0.780 1 (14.3) 18 (30.5) 5 (16.1) 0.259 6 (42.9) 12 (19.4) 6 (28.6) 0.165
 T4 9 (69.2) 48 (75.0) 16 (80.0) 6 (85.7) 41 (69.5) 26 (83.9) 8 (57.1) 50 (80.6) 15 (71.4)
Nodal status
 N0 6 (46.2) 24 (37.5) 2 (10.0) 0.041 2 (28.6) 23 (39.0) 7 (22.6) 0.281 9 (64.3) 19 (30.6) 4 (19.0) 0.017
 N1/N2 7 (53.8) 40 (62.5) 18 (90.0) 5 (71.4) 36 (61.0) 24 (77.4) 5 (35.7) 43 (69.4) 17 (81.0)
Stage
 III 6 (46.2) 19 (29.7) 3 (15.0) 0.151 2 (28.6) 20 (33.9) 6 (19.4) 0.351 6 (42.9) 16 (25.8) 6 (28.6) 0.445
 IV 7 (53.8) 45 (70.3) 17 (85.0) 5 (71.4) 39 (66.1) 25 (80.6) 8 (57.1) 46 (74.2) 15 (71.4)