Table 5.
Association between molecular marker expressions and radiological response in OSCC patients (n = 97).
| Molecular marker expressions | n | Radiological response |
p value | ||
|---|---|---|---|---|---|
| CR (n) (%) | PR (n) (%) | NR (n) (%) | |||
| Cyclin-D1 | |||||
| Negative | 13 | 4 (30.8) | 8 (61.5) | 1 (7.7) | < 0.001 |
| Moderate positive | 64 | 24 (37.5) | 36 (56.3) | 4 (6.3) | |
| Strong positive | 20 | 2 (10.0) | 7 (35.0) | 11 (55.0) | |
| EGFR | |||||
| Negative | 7 | 3 (42.9) | 3 (42.9) | 1 (14.3) | 0.014 |
| Moderate positive | 59 | 24 (40.7) | 24 (40.7) | 11 (18.6) | |
| Strong positive | 31 | 3 (9.7) | 24 (77.4) | 4 (12.9) | |
| p53 | |||||
| Negative | 14 | 12 (85.7) | 2 (14.3) | 0 (0.0) | < 0.001 |
| Moderate positive | 62 | 16 (25.8) | 44 (71.0) | 2 (3.2) | |
| Strong positive | 21 | 2 (9.5) | 5 (23.8) | 14 (66.7) | |
CR = complete response, PR = partial response, NR = No response.