Figure 2. Immunostaining shows changes to acetylated tubulin organization after a short (1 h) and longer (24 h) exposure to high levels of MI192 (10 μM).

(A) Representative images of PC3 cells stained for actin, α-tubulin and acetylated (Ac) tubulin at 1 h (control DMSO), 1 h of treatment with 10 μM MI192 and 2 h of treatment with 10 μM MI192. (B) Representative images of PC3 cells stained for actin (red), α-tubulin (green) and acetylated tubulin (Ac-tubulin, blue) after treatment for 24 h with 0.1% DMSO (control), 1 or 10 μM MI192.