Table 1.
Schedule of assessments.
| Assessment | Visit 1 screening | Visit 2 (baseline) | Check-up (2 weeks, call) | Visit 3 (1 month) | Visit 4 (3 months) | Visit 5 (6 months) | Visit 6 (9 months) | Visit 7 (12 months) | Early termination | Follow-up (24 months) |
|---|---|---|---|---|---|---|---|---|---|---|
| In- and exclusion criteria | x | |||||||||
| Consent | x | |||||||||
| Lab screening | x | |||||||||
| Drug treatment history | x | x | x | x | x | x | x | x | ||
| Withdrawal criteria | x | x | x | x | x | x | ||||
| CASH | x | |||||||||
| PANSS | x | x | x | x | x | x | x | x | ||
| Cognitive assessment | x | x | x | x | ||||||
| MRI scan | x | x | x | |||||||
| GAF | x | x | x | x | x | x | x | x | ||
| Physical examination | x | x | x | x | x | x | ||||
| Movement disorders | x | x | x | x | x | |||||
| Blood samples | x | x | x | x | x | x | ||||
| CTQ-SF | x | |||||||||
| CDSS | x | x | x | x | x | |||||
| Drug/alcohol use | x | x | x | x | ||||||
| Side effects simvastatin | x | x | x | x | x | x | x | |||
| Compliance monitoring | x | x | x | x | x | x |
Abbreviations: CASH = Comprehensive Assessment of Symptoms and History; PANSS = Positive and Negative Symptoms Scales; MRI = Magnetic Resonance Imaging; GAF = Global Assessment of Functioning; CTQ-SF = Childhood Trauma Questionnaire—Short Form; CDSS = Calgary Depression Scale for Schizophrenia.