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. 2015 Nov 2;16(11):26087–26124. doi: 10.3390/ijms161125942

Table 2.

The effects of some antioxidants/plants on NAFLD.

Models (Prevent/Treatment) Antioxidant/Plants Effects Dose (Dose-Effect) Bioactive Compounds References
Diabetic rats fed on a high fat thermolyzed diet (Prevent) Omega 3-polyunsaturated fatty acids ↑ SOD, CAT; ↓ triglycerides, non-esterified fatty acid, lipoperoxidation 3.0% in diet Omega 3-polyunsaturated fatty acids [108]
Mice fed with high-fat diet (Prevent and treatment) Moringa oleifera leaves; haw pectic oligosaccharide; Thymbra spicata ↑ GSH; ↓ ALT, AST, ALP, lipid peroxidation 50, 150 and 300 mg/kg b.w. (No dose–effect) Haw pectic oligosaccharide [109,110,111]
Liver damage in diet-induced atherosclerotic rats (Prevent) Tulbaghia violacea rhizomes ↓ LDH, AST, ALT, ALP, bilirubin antioxidation 100 mg/kg b.w. [112]
Rabbits with high-fat diet (Prevent) Apolipoprotein A–I ↑ SOD, GSH-Px; ↓ iNOS, MDA 15 mg/kg b.w. [113]
WeRats fed a high-fat diet (Prevent) Black cabbage sprout ↑ SOD, CAT, NADPH, GSH-Px, GRD GST 250 and 500 mg/kg b.w. (Dose–effect) [114]