Table 2.
Comparison of the inflammatory and angiogenic factors change among three grades.
| Factors | Grade I | Grade II | Grade III |
|---|---|---|---|
| IL-1β | 13.08% ± 5.75% | 67.65% ± 16.17% *** | 89.43% ± 8.53% *** |
| IL-6 | 12.29% ± 8.72% | 67.23% ± 17.63% *** | 84.16% ± 10.41% *** |
| COX-2 | 8.81% ± 6.87% | 92.69% ± 5.51% *** | 87.07% ± 7.64% *** |
| VEGF | 12.33% ± 4.60% | 75.78% ± 17.70% *** | 90.63% ± 4.45% *** |
| vWF | 5.96% ± 0.10% | 48.99% ± 23.15% | 70.21% ± 15.54% * |
IL, interleukin; COX, cyclooxygenase; VEGF, vascular endothelial growth factor; vWF, von Willebrand’s factor. Data are a percentage of positively stained cells, expressed as the mean ± standard deviation, and analyzed using one-way analysis of variance (ANOVA) and Bonferroni’s multiple comparison test (* p < 0.05, *** p < 0.001 compared with the grade I group).