Table 3.
SNP | Genotype | MY | FY | FP | PY | PP |
---|---|---|---|---|---|---|
c.-2012 T>C | CC (59) | 531.94 ± 102.58 A | 11.44 ± 4.38 | −0.05 ± 0.046 | 15.89 ± 3.06 A | −0.006 ± 0.015 |
CT (239) | 363.53 ± 75.15 A | 3.62 ± 3.39 | −0.07 ± 0.035 | 10.82 ± 2.37 A,B | −0.002 ± 0.010 | |
TT (198) | 192.65 ± 78.00 B | 0.91 ± 3.49 | −0.04 ± 0.036 | 7.10 ± 2.44 B | 0.012 ± 0.011 | |
p Value | 0.0002 ** | 0.0115 | 0.5315 | 0.0009 ** | 0.2303 | |
c.-2005 A>G | AA (275) | 242.80 ± 74.98 A | 6.24 ± 3.36 | 0.01 ± 0.023 | 9.72 ± 2.35 a | 0.003 ± 0.005 |
AG (183) | 361.60 ± 79.38 A,B | 6.77 ± 3.50 | 0.01 ± 0.030 | 12.42 ± 2.45 a,b | 0.003 ± 0.006 | |
GG (38) | 596.23 ± 118.54 B | 11.44 ± 5.11 | 0.01 ± 0.034 | 18.84 ± 3.58 b | −0.014 ± 0.012 | |
p Value | 0.0015 ** | 0.4639 | 0.7746 | 0.0048 * | 0.3535 | |
c.-1762 T>C | CC (71) | 620.74 ± 97.86 A | 15.84 ± 4.20 A,a | −0.05 ± 0.044 | 19.10 ± 2.94 A | −0.009 ± 0.015 |
CT (240) | 432.42 ± 75.59 A | 7.81 ± 3.41 b | −0.06 ± 0.035 | 14.93 ± 2.39 A | 0.006 ± 0.010 | |
TT (185) | 237.05 ± 77.76 B | 3.67 ± 3.47 B,b | −0.04 ± 0.036 | 9.35 ± 2.43 B | 0.012 ± 0.011 | |
p Value | <0.0001 ** | 0.0013 ** | 0.6539 | <0.0001 ** | 0.2924 | |
c.-1621 T>G | GG (48) | 500.63 ± 110.74 | 11.59 ± 4.68 | −0.04 ± 0.050 | 17.44 ± 1.19 A,a | 0.013 ± 0.017 |
GT (186) | 240.61 ± 77.84 | 4.37 ± 3.48 | −0.03 ± 0.036 | 8.99 ± 1.69 B,b | 0.013 ± 0.011 | |
TT (262) | 312.57 ± 74.72 | 6.77 ± 3.38 | −0.03 ± 0.034 | 10.39 ± 0.92 b | 0.005 ± 0.010 | |
p Value | 0.0279 | 0.1578 | 0.9389 | 0.0077 * | 0.6157 | |
c.-1376 G>A | AA (14) | 113.67 ± 167.77 A | −2.48 ± 6.82 A | −0.05 ± 0.075 | 3.64 ± 4.77 A | 0.007 ± 0.026 |
AG (162) | 158.20 ± 79.24 A | 1.22 ± 3.52 A | −0.03 ± 0.036 | 4.86 ± 2.47 A | 0.003 ± 0.011 | |
GG (320) | 459.43 ± 73.27 B | 9.06 ± 3.33 B | −0.05 ± 0.033 | 14.71 ± 2.33 B | 0.004 ± 0.010 | |
p Value | <0.0001 ** | 0.0009 ** | 0.6907 | <0.0001 ** | 0.9834 | |
c.-724 A>G | AA (185) | 547.23 ± 79.37 A | 10.08 ± 2.93 A | −0.07 ± 0.036 | 16.55 ± 2.49 A | −0.003 ± 0.011 |
AG (262) | 282.30 ± 73.85 B | 5.26 ± 2.75 AB | −0.03 ± 0.034 | 9.65 ± 2.34 B | 0.009 ± 0.010 | |
GG (49) | 36.21 ± 106.47 B | −3.01 ± 3.37 B | −0.03 ± 0.048 | 0.50 ± 3.15 C | 0.001 ± 0.016 | |
p Value | <0.0001 ** | 0.0016 ** | 0.2956 | <0.0001 ** | 0.3851 |
Bonferroni corrected significant level at p < 0.05 and p < 0.01 were 0.0083 and 0.0017, respectively; * p indicates the significant association after Bonferroni correction for multiple testing at the significance level of 0.05. ** p indicates the significant association after Bonferroni correction for multiple testing at the significance level of 0.01.; a,b within the same column with different superscripts means p < 0.05, A,B,C means p < 0.01.