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. 2015 Nov 9;16(11):26797–26812. doi: 10.3390/ijms161125990

Figure 4.

Figure 4

(a) WIPI4 may function to retrieve ATG9A from early autophagic vacuoles, and functional autophagosomes are formed with WIP4; and (b) the impairment of WIPI4 may lead to inhibition of the removal of ATG9A from early autophagic vacuoles and accumulation of early autophagic vacuoles. The red cross indicates loss of function. WIPI4: WD-repeat protein interacting with phosphoinositides 4.