Table 1.
Effective natural radiosensitizers for the treatment of cancer. These compounds act as radiosensitizers for cancer cells and, at the same time, radioprotectors for normal cells.
| Name | Types | Source | Radiosensitization | Target in Radiosensitization | Radioprotection | Target in Radioprotection |
|---|---|---|---|---|---|---|
| Curcumin | Polyphenol | Tumeric | Arrest, Apoptosis | NF-kB | Yes | NRF2, Antioxidant enzymes |
| Resveratrol | Polyphenol | Grapes | Apoptosis, Senescence | NF-kB, Cox-2, 5-LOX | Yes | Not determined |
| Genistein | Polyphenol | Soybean | Arrest, Apoptosis | Akt, Erk, Survivin, Cycline B, NF-kB | Yes | Not determined |
| Quercetin | Polyphenol | Ubiquitous | Arrest, Apoptosis | ATM | Yes | Not determined |