Table 4.
Aberrant miRNAs profile of Lin− cells expressed between benzene exposure group and the control group.
| miRNA_ID | Control | Benzene | |log2 (Fold Change)| | p-Value | Significance-Lable | Regulation |
|---|---|---|---|---|---|---|
| mmu-miR-17-3p | 83.7974 | 35.1372 | 1.253906 | 0.0114 | * | down |
| mmu-miR-28a-3p | 23.3702 | 8.7843 | 1.411671 | 0.0239 | * | down |
| mmu-miR-29a-3p | 121.5766 | 55.9239 | 1.120329 | 0.0201 | * | down |
| mmu-miR-29c-3p | 1009.316 | 466.1916 | 1.114384 | 0.00865 | ** | down |
| mmu-miR-33-5p | 1.6325 | 0 | 13.9948 | 0.0475 | * | down |
| mmu-miR-99a-5p | 624.7338 | 97.3232 | 2.682386 | 0.000487 | ** | down |
| mmu-miR-99b-5p | 13.7108 | 3.5659 | 1.942975 | 0.000161 | ** | down |
| mmu-miR-100-5p | 2226.083 | 288.6646 | 2.947041 | 0.0000316 | ** | down |
| mmu-miR-125a-5p | 61.9113 | 12.6981 | 2.28559 | 0.000129 | ** | down |
| mmu-miR-126a-3p | 200.2112 | 77.4933 | 1.369379 | 0.00904 | ** | down |
| mmu-miR-126a-5p | 30.3297 | 10.5238 | 1.527075 | 0.0106 | * | down |
| mmu-miR-128-1-5p | 1.4606 | 0 | 13.83427 | 0.000663 | ** | down |
| mmu-miR-141-3p | 90.3593 | 26.266 | 1.782477 | 0.000172 | ** | down |
| mmu-miR-181a-1-3p | 69.7313 | 20.508 | 1.76562 | 0.00506 | ** | down |
| mmu-miR-181d-5p | 1144.295 | 380.4057 | 1.588848 | 0.0000964 | ** | down |
| mmu-miR-181a-5p | 5882.768 | 2099.102 | 1.486723 | 0.024 | * | down |
| mmu-miR-181b-1-3p | 28.9987 | 6.5003 | 2.15741 | 0.0188 | * | down |
| mmu-miR-181c-3p | 134.7541 | 46.3262 | 1.540429 | 0.0112 | * | down |
| mmu-miR-188-5p | 0.9368 | 0 | 13.19353 | 0.0147 | * | down |
| mmu-miR-191-5p | 3285.317 | 1517.686 | 1.114159 | 0.0473 | * | down |
| mmu-miR-196b-5p | 34.9694 | 5.3101 | 2.719282 | 0.000407 | ** | down |
| mmu-miR-199b-5p | 7.0255 | 3.2044 | 1.132547 | 0.0498 | * | down |
| mmu-miR-203-3p | 125.1852 | 31.8607 | 1.974214 | 0.00191 | ** | down |
| mmu-miR-211-5p | 1.117 | 0 | 13.44734 | 0.00186 | ** | down |
| mmu-miR-224-5p | 8.4455 | 0 | 16.3659 | 0.000949 | ** | down |
| mmu-miR-324-3p | 59.3565 | 28.7012 | 1.048295 | 0.0416 | * | down |
| mmu-miR-342-5p | 11.1361 | 5.3923 | 1.046271 | 0.0338 | * | down |
| mmu-miR-342-3p | 403.5655 | 175.4169 | 1.202015 | 0.00359 | ** | down |
| mmu-miR-425-3p | 49.5631 | 20.7827 | 1.253883 | 0.024 | * | down |
| mmu-miR-455-5p | 103.3616 | 26.2759 | 1.975888 | 0.0167 | * | down |
| mmu-miR-455-3p | 14.3486 | 3.2959 | 2.122166 | 0.0034 | ** | down |
| mmu-miR-504-5p | 3.5127 | 0 | 15.10029 | 0.000458 | ** | down |
| mmu-miR-592-5p | 71.7493 | 5.0445 | 3.830182 | 0.000744 | ** | down |
| mmu-miR-671-3p | 8.6863 | 3.0213 | 1.523572 | 0.0323 | * | down |
| mmu-miR-872-5p | 68.65 | 26.0013 | 1.400676 | 0.00157 | ** | down |
| mmu-miR-874-3p | 5.8296 | 2.3421 | 1.315594 | 0.00755 | ** | down |
| mmu-miR-1291 | 5.1552 | 2.0874 | 1.304321 | 0.00577 | ** | down |
| mmu-miR-3060-5p | 1.1071 | 0 | 13.4345 | 0.000621 | ** | down |
| mmu-miR-5104 | 2.3198 | 1.0986 | 1.078334 | 0.0317 | * | down |
| mmu-miR-5107-3p | 1.2706 | 0 | 13.63322 | 0.00982 | ** | down |
| mmu-miR-5120 | 1.1922 | 0 | 13.54134 | 0.0195 | * | down |
| mmu-miR-6988-3p | 5.0244 | 1.9226 | 1.385893 | 0.00503 | ** | down |
| mmu-miR-7043-3p | 22.7206 | 11.078 | 1.036303 | 0.00864 | ** | down |
| mmu-miR-7649-5p | 8.3457 | 2.3483 | 1.829416 | 0.0346 | * | down |
| mmu-let-7i-3p | 1.0463 | 0 | 13.35301 | 0.0185 | * | down |
| mmu-miR-34a-5p | 15.3215 | 83.1308 | 2.439826 | 0.0075 | ** | up |
| mmu-miR-129b-5p | 0 | 3.7399 | 15.19071 | 0.00879 | ** | up |
| mmu-miR-451a | 4681.085 | 14232.5 | 1.604274 | 0.0241 | * | up |
| mmu-miR-144-5p | 46.7118 | 120.2277 | 1.36391 | 0.0251 | * | up |
| mmu-miR-129b-3p | 4.4096 | 18.7862 | 2.090954 | 0.0211 | * | up |
Lin− cells from two mice were pooled as one sample, three samples per group were analyzed for miRNAs profile. n = 3 for each group. * p < 0.05. ** p < 0.01.