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Effect of shikimic acid on the amounts of K+ (A) and the cell nucleotide (B) leakage from S. aureus American type culture collection (ATCC) 6538. Data are expressed as mean ± standard deviation. ** p < 0.01, compared with control. Minimal inhibition concentration (MIC) is defined to be the lowest concentration of shikimic acid (SA) capable of inhibiting the tested bacterial visible growth.
