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. 2015 Nov 18;16(11):27625–27639. doi: 10.3390/ijms161126046

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Particle size distribution of NPs-TBAs at 25 °C recorded by DLS. The mixtures of TBA1 and TBA2 NPs (left) and O⁶−MeG-TBA1 and TBA2 NPs (right) are displayed in dashed blue, while the same NP mixtures in the presence of α-thrombin are represented in orange. Each image is the result of the combination of two DLS experiments with and without α-thrombin. The individual DLS measurements are shown in Figure S4 (ESI). In all cases, the molar ratio of α-thrombin: TBAs was 0.5:1. From top to bottom: (a) AuNP, (b) SPIONs and (c) AuSPION.