Table 3.

Logistic regression models of the likelihood of better compliance with treatment

		Model 1a			Model 2b
Variable			95 % CI for OR			95 % CI for OR
Category		OR	(lower -upper)	p-value	OR	(lower-upper)	p-value
Sex
Female		1.04	(0.85–1.26)	0.721
Polypharmacy
=<2 (Ref.)				<0.001			<0.001
2–2.6		2.11	(1.51–2.96)	<0.001	2.10	(1.51–2.93)	<0.001
2.7–4.3		4.67	(3.39–6.41)	<0.001	4.48	(3.30–6.10)	<0.001
>4.3		8.85	(6.33–12.35)	<0.001	8.20	(6.02–11.11)	<0.001
Age group
Under 35 (Ref.)				0.389
35–64		1.00	(0.75–1.33)	0.991
Over 65		0.87	(0.63–1.20)	0.392
Diagnosis recorded
None (Ref.)				<0.001			<0.001
Only anxiety		1.41	(1.13–1.75)	0.002	1.45	(1.17–1.80)	<0.001
Only depression		1.58	(1.26–1.97)	<0.001	1.63	(1.31–2.03)	<0.001
Ambos		1.74	(1.25–2.42)	0.001	1.84	(1.33–2.54)	<0.001
Drug dispensed
Amitriptyline		0.81	(0.66–1.00)	0.047
Paroxetine		0.57	(0.48–0.68)	<0.001	0.57	(0.48–0.68)	<0.001
Fluoxetine		1.09	(0.91–1.30)	0.335
Citalopram		1.05	(0.88–1.25)	0.604
Sertraline		1.11	(0.93–1.34)	0.256
Venlafaxine		1.92	(1.59–2.30)	<0.001	1.99	(1.66–2.39)	<0.001
Clomipramine		1.78	(1.40–2.27)	<0.001	1.80	(1.41–2.28)	<0.001
Mirtazapine		1.39	(1.10–1.75)	0.005	1.44	(1.14–1.81)	0.002
Trazodone		0.58	(0.40–0.83)	0.003	0.60	(0.42–0.85)	0.005
Maprotiline		1.61	(1.07–2.43)	0.023	1.64	(1.09–2.46)	0.018
Imipramine		1.70	(0.86–3.38)	0.129
Nortriptyline		1.41	(0.56–3.52)	0.462
Fluvoxamine		1.45	(0.94–2.24)	0.089
Hosmer & Lemeshow test				0.003			0.781
Discrimination (Area Under Curve COR)		0.749		<0.001	0.729		<0.001

^aModel 1: Multivariate association of compliance with all factors (the complete model)

^bModel 2: Multivariate association of compliance with all statistically significant factors

Ref.: Reference category