Table 2.
T = −3 Mean (SD) | T = −2 Mean (SD) | T = −1 Mean (SD) | Mean annual before (SD) | T = +1 Mean (SD) | T = +2 Mean (SD) | T = +3 Mean (SD) | Mean annual after (SD) | Mean dif (SD) | P value difference | ||
---|---|---|---|---|---|---|---|---|---|---|---|
GPs | Primary care patients | – | 98 (103) | 104 (103) | 102 (103) | 129 (120) | 125 (130) | 127 (127) | 127 (125) | 25 (121) | 0.15 |
Secondary care patients | 93 (90) | 102 (97) | 142 (119) | 122 (110) | 147 (165) | 155 (158) | 168 (181) | 154 (166) | 32 (146) | ||
Primary care controls | – | 67 (67) | 74 (94) | 72 (87) | 68 (78) | 68 (75) | 75 (95) | 70 (81) | −2 (82) | 0.13 | |
Secondary care controls | 74 (88) | 77 (99) | 78 (98) | 77 (97) | 78 (96) | 80 (95) | 83 (96) | 80 (2) | 3 (96) | ||
Hospital specialistsa | Primary care patients | – | 1168 (2645) | 1087 (2520) | 1111 (2551) | 1345 (2572) | 1391 (2932) | 1544 (2822) | 1409 (2758) | 298 (2719) | <0.01× |
Secondary care patients | 1139 (3780) | 1063 (2763) | 1500 (3713) | 1303 (3450) | 3695 (6400) | 2678 (6198) | 2815 (5783) | 3173 (6230) | 1870 (5269) | ||
Primary care controls | – | 591 (1812) | 874 (2504) | 792 (2325) | 822 (2328) | 1048 (2882) | 1051 (2553) | 955 (2585) | 164 (2537) | 0.16 | |
Secondary care controls | 1259 (4742) | 1319 ± 4806) | 1342 (6006) | 1322 (5457) | 1294 (8598) | 1333 (4987) | 1441 (5071) | 1337 (5149) | 15 (5277) | ||
Medication | Primary care patients | – | 401 (657) | 448 (680) | 434 (672) | 522 (792) | 580 (911) | 751 (2087) | 598 (1269) | 164 (1177) | <0.01× |
Secondary care patients | 477 (992) | 545 (1143) | 630 (1227) | 579 (1169) | 939 (1707) | 999 (1797) | 1163 (2087) | 1005 (1822) | 426 (1587) | ||
Primary care controls | – | 398 (783) | 481 (1360) | 457 (1220) | 449 (1252) | 471 (1231) | 490 (1435 | 466 (1291) | 10 (1278) | 0.97 | |
Secondary care controls | 525 (1398) | 555 (1390) | 558 (1452) | 552 (1434) | 561 (1597) | 558 (1346) | 561 (1304) | 560 (1459) | 8 (1445) | ||
Totala | Primary care patients | – | 1667 (2922) | 1640 (2898) | 1648 (2898) | 1996 (2923) | 2096 (3269) | 2423 (3746) | 2134 (3258) | 486 (3192) | <0.01× |
Secondary care patients | 1708 (4080) | 1710 (3204) | 2272 (4145) | 2003 (3863) | 4781 (7058) | 3832 (6951) | 4146 (6670) | 4331 (6958) | 2328 (5888) | ||
Primary care controls | – | 1056 (2236) | 1429 (3052) | 1320 (2840) | 1338 (2872) | 1586 (3369) | 1616 (3156) | 1492 (3120) | 171 (3068) | 0.26 | |
Secondary care controls | 1858 (5295) | 1950 (5376) | 1978 (6501) | 1951 (6002) | 1933 (5893) | 1971 (5490) | 2086 (5558) | 1976 (5692) | 26 (5812) |
aExcluding psychiatric care; ×, significant difference at alpha = 0.05
T = −3 indicates three years before diagnosis, T = +1 one year after diagnosis and so forth