Table 5.
Results of Main Linear Regression Models
Predictor | Left Putamen | Left Post-Central Gyrus | Left Anterior Cingulate | Right Parahippocampal Gyrus | Left Caudate Tail | Left Middle Frontal Gyrus | Left Inferior Frontal Gyrus | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
β | t | β | t | β | t | β | t | β | t | β | t | β | t | |
Sex | 0.258 | 1.436 | 0.038 | 0.206 | −0.203 | −1.184 | 0.043 | 0.255 | 0.209 | 1.156 | −0.140 | −0.742 | −0.245 | −1.308 |
Ethnicity | −0.808 | −3.986*** | 0.755 | 3.63*** | −0.229 | −1.181 | −0.039 | −0.203 | −0.043 | −0.210 | 0.142 | 0.663 | 0.034 | 0.161 |
GPS | −0.421 | −4.345*** | 0.438 | 4.411*** | −0.074 | −0.798 | −0.110 | −1.194 | −0.124 | −1.269 | 0.051 | 0.504 | 0.075 | 0.738 |
Life Events | 0.141 | 1.435 | 0.168 | 1.676# | 0.501 | 5.347*** | 0.095 | 1.029 | 0.199 | 2.024* | 0.040 | 0.384 | −0.078 | −0.760 |
GPS x Sex | 0.197 | 1.177 | −0.129 | −0.749 | 0.202 | 1.263 | −0.237 | −1.494 | −0.221 | −1.310 | 0.136 | 0.772 | 0.047 | 0.267 |
LE x Sex | 0.298 | 1.635 | −0.099 | −0.529 | 0.203 | 1.167 | 0.075 | 0.433 | 0.183 | 1.000 | −0.104 | −0.540 | −0.321 | −1.689# |
GPS x Ethnicity | 0.107 | 0.562 | 0.272 | 1.391 | 0.235 | 1.285 | −0.170 | −0.940 | −0.062 | −0.325 | 0.455 | 2.259* | 0.426 | 2.137* |
LE x Ethnicity | −0.179 | −0.876 | 0.447 | 2.134* | 0.417 | 2.134* | −1.048 | −5.417*** | −0.730 | −3.550** | 0.891 | 4.136*** | 0.326 | 1.526 |
GPS x LE | −0.348 | −2.693*** | 0.245 | 1.844# | 0.167 | 1.348 | −0.755 | −6.161*** | −0.631 | −4.853*** | 0.665 | 4.876*** | 0.500 | 3.703*** |
Depressive Symptoms | 0.041 | 0.444 | 0.020 | 0.207 | −0.031 | −0.352 | −0.101 | −1.155 | −0.150 | −1.621 | 0.029 | 0.298 | 0.166 | 1.721# |
Anxiety Symptoms | 0.095 | 0.934 | −0.016 | −0.154 | 0.366 | 3.759*** | 0.040 | 0.413 | 0.093 | 0.903 | 0.031 | 0.292 | −0.192 | −1.799# |
Externalizing Symptoms | −0.141 | −1.290 | −0.294 | −2.612* | −0.298 | −2.843** | 0.069 | 0.669 | −0.094 | −0.852 | −0.030 | −0.260 | −0.042 | −0.365 |
Emotion Regulation | 0.105 | 1.117 | −0.175 | −1.809# | −0.106 | −1.171 | 0.167 | 1.865# | 0.036 | 0.384 | −0.051 | −0.511 | −0.056 | −0.570 |
R2 | 0.313 | 0.276 | 0.372 | 0.383 | 0.304 | 0.236 | 0.251 | |||||||
Adjusted R2 | 0.229 | 0.189 | 0.296 | 0.308 | 0.220 | 0.143 | 0.160 | |||||||
Model F | 3.746*** | 3.145** | 4.882*** | 5.114*** | 3.600*** | 2.544** | 2.752** |
Standardized regression coefficients (β) and their associated t-values are presented for all predictors in the main regression results predicting all seven regions of interest. Model R2, adjusted R2, and model F values are presented for each model. Effects that identified each region are shaded gray. Effects with p<0.10 are in bold. GPS= genetic profile scores, LE= life events.
GxE effect not significant at whole-brain threshold level.
p<0.10,
p<0.05,
p<0.01,
p<0.001