Table 2.
Variable | Group A: IV iron alone (n = 34) |
Group B: combined therapy (n = 47) |
||||
---|---|---|---|---|---|---|
before | after | p value | before | after | p value | |
Hb, g/dl | 10.6 ± 1.1 | 11.9 ± 1.1 | >0.001 | 10.2 ± 0.9 | 12.4 ± 1.3 | >0.001 |
Hematocrit, % | 31.9 ± 3.4 | 35.2 ± 3.9 | >0.001 | 31.4 ± 6.7 | 37.1 ± 4.2 | >0.001 |
MCV, fl | 85.6 ± 4.5 | 87.5 ± 4.3 | 0.001 | 88.7 ± 7.2 | 90.3 ± 9.6 | 0.021 |
MCH, pg/cell | 28.6 ± 2.2 | 29.7 ± 1.9 | >0.001 | 29.8 ± 2.5 | 30.2 ± 2.5 | 0.043 |
MCHC, g/dl | 33.3 ± 1.1 | 33.7 ± 0.9 | 0.066 | 33.5 ± 1.1 | 33.5 ± 0.9 | 0.979 |
Platelets, ×109/l | 225 ± 69 | 199 ± 51 | 0.002 | 219 ± 63 | 216 ± 54 | 0.540 |
Ferritin, ng/ml | 146 ± 112 | 454 ± 271 | >0.001 | 148 ± 156 | 310 ± 203 | >0.001 |
Serum iron, µg/dl | 51.1 ± 16 | 73.6 ± 23 | >0.001 | 49.7 ± 21 | 60.1 ± 18 | 0.004 |
Transferrin, µg/dl | 246 ± 62 | 222 ± 51 | 0.015 | 248 ± 61 | 218 ± 48 | >0.001 |
Transferrin saturation, % | 21.0 ± 9.7 | 31.2 ± 9.3 | >0.001 | 19.8 ± 10.5 | 26.1 ± 10.5 | >0.001 |
Data are expressed as the mean ± SD. MCHC = MCH concentration.