Table 2.
Genotype and allele frequency distribution in the study groups
| Genotype/allele | Control p±sp (CI) | EH p±sp (CI) | Stroke p±sp (CI) | EH p OR (CIor) | Stroke p OR (CIor) |
|---|---|---|---|---|---|
| CXCL1 | |||||
| G/G | 26.47±2.52 (21.61 – 31.79) | 34.85± 3.07 (28.85–41.24) | 26.76 ± 5.25 (16.94 – 38.59) | 0.039 1.49 (1.03 – 2.15) | 1.000 |
| A/G | 53.92 ±2.85 (48.16 – 59.61) | 46.47 ± 3.21 (40.05 – 52.99) | 56.34 ± 5.89 (44.05 – 68.09) | 0.086 | 0.792 |
| A/A | 19.61 ±2.27 (15.31 – 24.51) | 18.67± 2.51 (13.96 – 24.18) | 16.9± 4.45 (9.05 – 27.66) | 0.827 | 0.738 |
| G | 53.43 ±2.02 (49.39 – 57.44) | 58.09± 2.25 (53.54 – 62.54) | 54.93 ± 4.18 (46.36 – 63.28) | 0.126 | 0.780 |
| A | 46.57 ±2.02 (42.56 – 50.61) | 41.91± 2.25 (37.46 – 46.46) | 45.07 ± 4.18 (36.72 – 53.64) | 0.126 | 0.780 |
| CXCR2 | |||||
| T/T | 34.1± 2.71 (28.79 – 39.72) | 30.47± 3.02 (24.63 – 36.82) | 32.86 ± 5.61 (22.09 – 45.12) | 0.404 | 0.889 |
| T/C | 46.56 ±2.86 (40.85 – 52.33) | 51.5 ± 3.27 (44.89 – 58.08) | 60 ±5.86 (47.59 – 71.53) | 0.259 | 0.047 1.72 (1.01 – 2.92) |
| C/C | 19.34 ±2.26 (15.06 – 24.23) | 18.03± 2.52 (13.31 – 23.57) | 7.14± 3.08 (2.36 – 15.89) | 0.73 | 0.013 0.32 (0.12 – 0.83) |
| T | 57.38 ±2 (53.34 – 61.34) | 56.22± 2.3 (51.58 – 60.78) | 63.64 ± 4.19 (54.82 – 71.83) | 0.710 | 0.206 |
| C | 42.62 ±2 (38.66 – 46.66) | 43.78± 2.3 (39.22 – 48.42) | 36.36 ± 4.19 (28.17 – 45.18) | 0.710 | 0.206 |
| CCL18 | |||||
| T/T | 18.61 ±2.35 (14.18 – 23.74) | 33.8 ± 3.22 (27.52 – 40.53) | 24.24 ± 5.27 (14.54 – 36.36) | 0.0002 2.23 (1.47 – 3.38) | 0.305 |
| T/C | 53.65 ±3.01 (47.55 – 59.67) | 44.44± 3.38 (37.7 – 51.34) | 51.52 ± 6.15 (38.88 – 64.01) | 0.046 0.67 (0.47 – 0.96) | 0.785 |
| C/C | 27.74 ±2.7 (22.52 – 33.44) | 21.76± 2.81 (16.45 – 27.86) | 24.24 ± 5.27 (14.54 – 36.36) | 0.142 | 0.645 |
| T | 45.44 ±2.13 (41.21 – 49.71) | 56.02± 2.39 (51.19 – 60.76) | 50 ±4.35 (41.18 – 58.82) | 0.001 1.53 (1.19 – 1.97) | 0.382 |
| C | 54.56 ±2.13 (50.29 – 58.79) | 43.98± 2.39 (39.24 – 48.81) | 50 ±4.35 (41.18 – 58.82) | 0.001 0.65 (0.5 – 0.84) | 0.382 |
| CCR2 | |||||
| V/V | 74.84 ±2.48 (69.58 – 79.6) | 66.52± 3.13 (59.97 – 72.63) | 75.38 ± 5.34 (63.13 – 85.23) | 0.042 0. 67 (0.46 – 0.98) | 1.000 |
| V/I | 23.86 ±2.44 (19.19 – 29.04) | 31.28± 3.08 (25.31 – 37.75) | 23.08 ± 5.23 (13.53 – 35.19) | 0.061 | 1.000 |
| I/I | 1.31 ± 0.65 (0.36 – 3.31) | 2.2 ±0.97 (0.72 – 5.07) | 1.54± 1.53 (0.04 – 8.28) | 0.506 | 1.000 |
| V | 86.76 ±1.37 (83.82 – 89.35) | 82.16± 1.8 (78.32 – 85.57) | 86.92 ± 2.96 (79.89 – 92.19) | 0.047 0.7 (0.5 – 0.98) | 1.000 |
| I | 13.24 ±1.37 (10.65 – 16.18) | 17.84± 1.8 (14.43 – 21.68) | 13.08 ± 2.96 (7.81 – 20.11) | 0.047 1.42 (1.02 – 1.99) | 1.000 |
p ± sp = Genotype/allele frequency ± standard error; p = level of significance (p < 0.05 are given in bold).