Table 3.

Allele and genotype combinations most significantly associated with stroke

CXCR2 rs1126579	CCR5 rs333	CCL2 rs1024611	IL8 rs4073	CX3CR1 rs3732378	CCL18 rs8073066	Control, %	Stroke, %	Fisher's p value	Pperm	OR	CIOR
T	I/I					63.92	82.09	0.0028	0.016	2.59	1.32 – 5.08
C/C		A				6.15	19.61	0.005	0.026	0.27	0.09 – 0.77
T	I					92.54	79.22	0.006	0.032	3.25	1.25 – 8.50
C/C			C			4.76	17.33	0.0067	0.032	0.24	0.07 – 0.80
C/C				T		6.25	19.05	0.0075	0.035	0.28	0.10 – 0.82
T		G			A	43.75	27.06	0.0082	0.035	2.1	1.19 – 3.69

P_perm = Standard permutation p value.