Table 2.

Variable and two levels

	Low level (−1)	High level (+1)
Independent variables
A = CCS concentration (%)	4	8
B = MCC concentration (%)	20	40
C = compression force (ton)	2	4
Dependent variables
Y1 = DT
Y2 = %DR

Abbreviations: CCS, croscarmellose sodium; MCC, microcrystalline cellulose; DT, disintegration time; DR, drug release.