Table 1.
Characteristic | FAST-1 | FAST-2 | ||
---|---|---|---|---|
Icatibant (N = 27) | Placebo (N = 29) | Icatibant (N = 36) | Tranexamic Acid (N = 38) | |
Sex — no. (%) | ||||
Male | 11 (41) | 8 (28) | 12 (33) | 15 (39) |
Female | 16 (59) | 21 (72) | 24 (67) | 23 (61) |
Age — yr | 34.8±9.8 | 34.9±11.4 | 40.4±13.6 | 41.9±12.4 |
Weight — kg | 80.3±21.1 | 76.0±21.9 | 80.1±16.1 | 74.2±15.6 |
Type of HAE attack — no. | ||||
Cutaneous | 14 | 13 | 24 | 23 |
Abdominal | 13 | 16 | 12 | 15 |
No. of attacks in previous 6 mo — median (range) | ||||
Cutaneous | 6 (1–44) | 6 (1–50) | 6 (1–24) | 5 (1–25) |
Abdominal | 3 (1–24) | 5 (2–16) | 3 (1–15) | 3 (1–72) |
Cutaneous and abdominal | 2 (1–40) | 5 (1–12) | 4 (1–24) | 2 (1–12) |
Laryngeal | 1 (1–4) | 1 (1–9) | 2 (1–7) | 1 (1–6) |
Plus–minus values are means ±SD. HAE denotes hereditary angioedema.