Figure 6.
In vitro cytotoxicity of free drugs and various NPs against Colon-26 cells, determined by MTT assays. (a) Cytotoxicity of different concentrations of empty cationic NPs towards Colon-26 cells after incubation for 24 and 48 h. Cytotoxicity of free drugs and various NPs at different concentrations towards Colon-26 cells after incubation for 24 h (b) and 48 h (c). (d) Cytotoxicity of various cationic CPT/CUR-NPs with different weight ratios after incubation for 24 and 48 h. Triton X-100 (0.1%) was used as a positive control to produce a maximum cell death rate (100%); cell culture medium was used as a negative control (death rate defined as 0%). Cytotoxicity is given as the percentage of viable cells remaining after treatment. Each point represents the mean ± S.E.M. (n = 5).