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Schematic representation of gene interactions in cells treated with the combination of Olaparib (5μM) and Trabectedin (250pM), obtained after performing IPA. Over-expressed genes are highlighted in red, and the down-regulated genes are highlighted in green. The central genes involved in HR machinery are highlighted in color, such as BRAC1, EXO1, RAD51 and BRCA2, among others.
