Table 1. Proliferation assays show that the combination of Olaparib and Trabectedin is synergistic in all ES cell lines with the exception of A4573 and WE68, where the CIs are almost additive (values close to 1).
| Cell lines | CI | Effects |
|---|---|---|
| RDES | 0.73 | Synergism |
| WE68 | 0.92 | Nearly additive |
| STAET-2.1 | 0.49 | Synergism |
| RM82 | 0.69 | Synergism |
| TC71 | 0.4 | Synergism |
| SK-N-MC | 0.008 | Synergism |
| CADO | 0.4 | Synergism |
| A673 | 0.77 | Synergism |
| A4573 | 0.93 | Nearly additive |
| STAET-1 | 0.64 | Synergism |
| SJRH | 0.11 | Synergism |