TABLE 4.
Multivariate analysis of outcomes in black and white patients (n = 602)
| Hazard Ratio (95% Confidence Interval)
|
||||
|---|---|---|---|---|
| Local Control | Freedom From Distant Metastasis | Progression Free Survival | Overall Survival | |
| Black | 0.73 (0.52–1.05), | 0.90 (0.66–1.83), | 0.90 (0.80–1.52), | 1.11 (0.71–1.77), |
| P value | .09 | .68 | .52 | .66 |
| Tumor stage III–IV | 1.59 (0.99–2.70) | 4.43 × 109 (7.54–7.79×1041), | 2.37 (1.48–4.03), | 2.87 (1.47–6.34), |
| P value | .05 | < .0001 | .0002 | .001 |
| ≥ 2 drinks per day | 1.30 (0.87–1.99), | 3.53 (1.77–8.12), | 1.46 (1.03–2.10), | 1.77 (1.08–3.06), |
| P value | .20 | .0001 | .03 | .02 |
| RT delay >5 days | 1.41 (0.96–2.02), | N.A. | 1.27 (0.92–1.73), | 1.31 (0.84–1.98), |
| P value | .08 | .15 | .23 | |
| Post-operative RT | 0.55 (0.36–0.81), | N.A. | 0.64 (0.46–0.89), | 0.62 (0.39–0.96), |
| P value | .003 | .007 | .03 | |
| Era of RT (1990–97 referent) | ||||
| 1998–2004 | 0.93 (0.59–1.51) | 2.19 (1.03–5.41) | 1.17 (0.76–1.84) | 1.53 (0.81–3.08) |
| P value | .76 | .04 | .48 | .20 |
| 2005–2012 | 1.23 (0.76–2.03) | 2.69 (1.19–6.91) | 1.68 (096–2.97) | 2.12 (0.96–4.87) |
| P value | .41 | .02 | .07 | .06 |
| Truncated RT course | N.A. | 4.08 (1.40–9.53), | N.D. | N.D. |
| P value | .01 | |||
| Node levels IV/V/SCV | N.A. | 1.79 (1.05–2.98), | 1.42 (0.98–2.03), | 1.31 (0.80–2.48), |
| P value | .03 | .06 | .27 | |
| KPS ≥ 70 | N.A. | 1.17 (0.48–3.89), | 0.90 (0.53–1.65), | 1.02 (0.49–2.48), |
| P value | .76 | .71 | .97 | |
| Intensity modulated RT | N.A. | N.A. | 1.06 (0.73–1.57) | 1.15 (0.69–1.90) |
| P value | .73 | 0.59 | ||
| > 10 pack-years | N.A. | N.A. | N.A. | 1.36 (0.60–3.93), |
| P value | .49 | |||
KPS = Karnofsky Performance Status.
N.A. = Not Applicable due to P value > .1 on univariate analysis.
N.D. = Not Done due to too few events for analysis.