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. 2015 Oct 20;3:e1340. doi: 10.7717/peerj.1340

Table 2. Estimated risk of becoming a newly incident extra-medical user of prescription pain relievers, stratified by age at assessment and survey year-pair.

Age- and time-specific incidence estimates (A), 95% confidence intervals (B), and age-specific meta-analysis summary estimates. Data from Restricted-Use Data Analysis System subsamples of the National Surveys on Drug Use and Health, United States 2002–2013.

Year pair 12–13 y 14–15 y 16–17 y 18–19 y 20–21 y
(A) Estimated risk of becoming a newly incident user (per 100)
2002–2003 1.3 4.4 6.3 5.7 3.5
2004–2005 1.4 3.7 5.9 4.9 3.7
2006–2007 1.2 3.4 5.2 5.6 3.3
2008–2009 1.1 3.9 5.3 5.0 3.4
2010–2011 1.1 3.2 4.9 4.3 2.8
2012–2013 0.8 2.5 3.8 3.3 3.0
(B) 95% confidence intervals for estimates in (A) (per 100)
2002–2003 1.1, 1.5 4.1, 4.8 5.9, 6.8 5.2, 6.2 3.1, 3.9
2004–2005 1.2, 1.6 3.4, 4.0 5.5, 6.3 4.5, 5.4 3.3, 4.1
2006–2007 1.1, 1.4 3.1, 3.7 4.9, 5.6 5.2, 6.1 2.9, 3.7
2008–2009 0.9, 1.3 3.6, 4.2 4.9, 5.7 4.6, 5.4 3.1, 3.9
2010–2011 1.0, 1.3 2.9, 3.5 4.6, 5.3 3.9, 4.7 2.5, 3.2
2012–2013 0.7, 1.1 2.2, 2.9 3.4, 4.2 2.9, 3.8 2.5, 3.5
Meta-analysis summary estimates & 95% confidence intervals (per 100)a 1.2 (1.0, 1.3) 3.5 (3.0, 4.0) 5.2 (4.5, 5.9) 4.8 (4.1, 5.5) 3.3 (3.1, 3.5)b

Notes.

a

Supplemental Information 4 provides additional information about I-squared.

b

Here, the I-squared statistic has 0.05 > p > 0.15 so the 95% CI are from ‘fixed effects’ estimation; the corresponding ‘Random Effects’ interval is 3.0, 3.6. All other meta-analytic 95% CI are from ‘random effects’ estimation (due to I-squared p < 0.05).