Figure 1. Highly ortho- chlorinated PCBs 154, 155, and 184 reduce PON1 activity in rat liver and serum.
Male and female rats received injections of PCB154 low: 2× 50 μmol/kg, PCB154 high: 2× 100 μmol/kg, PCB155: 2× 100 μmol/kg), PCB184: 2× 100 μmol/kg. Results are expressed as mean ± SEM (n=6), Statistical significance: P<0.05, a. treatment vs corn oil, b. female vs corresponding male (serum only).