Table 1.
LPK NPs | Lipid composition | Surface charge (mV ± SD) | Size (nm ± SD) | Polydispersity |
---|---|---|---|---|
LPK− | DOPC:cholesteral:DSPE-PEG2000 (w/w 8:0.5:1.5) | −11.7 ± 1.8 | 127.5 ± 5.2 | 0.18 ± 0.04 |
LPK+ | DOTAP:cholesteral:DSPE-PEG2000 (w/w 8:0.5:1.5) | 24.7 ± 0.5 | 123.0 ± 7.4 | 0.20 ± 0.05 |
LPKpH | DOPE:CHEMS:DSPE-PEG2000 (w/w 6.5:2.0:1.5) | 14.2 ± 1.4 | 120.1 ± 8.8 | 0.21 ± 0.02 |