In general, de novo fatty acid synthesis is decreased in the liver and pancreas, which also appears in the serum due to transport, in most part, from the liver. Interestingly, newly synthesized stearate in liver (B) does not appear in the serum of ethanol treated animals (A) demonstrating a severe defect in long chain saturated fatty acid transport from the ethanol exposed liver. The “Y” axis shows Fraction of New Synthesis of each fatty acid as percent of the total corresponding fatty acid pool in tissues as indicated on “X”. (Palm=palmitate, Stear=stearate; Average+SD; n=3; *p<0.05)