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. 2015 Nov 24;85(21):1886–1893. doi: 10.1212/WNL.0000000000002147

Figure 2. Connective tissue and MFA evaluation in untreated and treated patients.

Figure 2

(A) Connective tissue in patients not treated with steroids (40 patients) shows a more consistent and rapid increase in fibrotic tissue between 6 and 7 years of age. At the age of 7, the proportion rises to 29.85% (SD 7.75) corresponding to an increase of more than 10% in 1 year. Connective tissue in patients treated with steroids (16 patients aged 7–10 years) ranged from 22.38% (SD 8.5) to 29.85% (SD 6.49) with increasing age. (B) MFA in the steroid-free group (40 patients). The values remained quite stable between 1 and 6 years of age (range from 79.14% [SD 0.05] to 85.04% [SD 0.06]), but a reduction was evident in patients older than 7 years (values between 69.84% [SD 0.1] and 74.47% [SD 0.05]). In the steroid-treated group (16 patients aged 7–10 years), MFA values ranged between 68.44% (SD 0.08) and 77.09% (SD 0.13).