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. 2015 Nov 24;85(21):1834–1842. doi: 10.1212/WNL.0000000000002151

Figure 3. CSF levels of angiogenesis biomarkers (cohorts 2 and 3).

Figure 3

(A–C) Placental growth factor (PlGF), vascular endothelial growth factor (VEGF)/sVEGFR-1 ratio, and PlGF/sVEGFR-1 ratio are higher in patients with Parkinson disease with dementia (PDD)/patients with dementia with Lewy bodies (DLB) than in controls in cohort 2. (D, E) VEGF and PlGF levels are elevated in patients with Parkinson disease without dementia (PDND) and patients with PDD compared to controls in cohort 3 with neuropathologically confirmed diagnosis. Angiogenesis biomarkers were skewed and therefore ln-transformed before statistical analyses; p values are from analysis of covariance adjusting for age and sex as described in the Methods; data are presented as mean ± 95% confidence interval.