Table 3.
Demographics of study groups. Sepsis Code gro up patients had ICD9-CM codes for severe seps is or septic shock. Combination Code group patients had ICD9-CM codes for infection plus organ dysfunction. Control group 1 patients did not have codes for sepsis, infection, or organ dysfunction and were matched to Sepsis Code patients on date of hospital admission. Control group 2 had ICD9-CM codes for infection but not sepsis or organ dysfunction, and were matched to Sepsis Code patients on proportion admitted to the intensive care unit vs. regular inpatient floor. Use of mechanical ventilation and vasoactive medications are on the sepsis day only. For length of stay variables, the median is presented with interquartile range in brackets.
| N(%) | Total | Sepsis Codes | Combination Codes | Control Group 1 | Control Group 2 | P |
|---|---|---|---|---|---|---|
| N Patients | 431 | 120 | 106 | 102 | 103 | |
| Female | 196 (45.5) | 53 (44.2) | 55 (51.9) | 41 (40.2) | 47 (45.6) | 0.394 |
| Age | ||||||
| 61d–<1 year | 83 (19.3) | 17 (14.2) | 25 (23.6) | 10 (9.8) | 31 (30.1) | 0.005 |
| 1 year–4 years | 130 (30.2) | 38 (31.7) | 27 (25.5) | 38 (37.3) | 27 (26.2) | |
| 5 years–9 years | 81 (18.8) | 21 (17.5) | 22 (20.8) | 26 (25.5) | 12 (11.7) | |
| 10 years–14 years | 61 (14.2) | 22 (18.3) | 11 (10.4) | 16 (15.7) | 12 (11.7) | |
| 15–<19 years | 76 (17.6) | 22 (18.3) | 21 (19.8) | 12 (11.8) | 21 (20.4) | |
| Race | ||||||
| Non-Hispanic White | 258 (59.9) | 71 (59.2) | 65 (61.3) | 58 (56.9) | 64 (62.1) | 0.753 |
| Non-Hispanic Black | 64 (14.8) | 16 (13.3) | 14 (13.2) | 19 (18.6) | 15 (14.6) | |
| Hispanic | 60 (13.9) | 18 (15) | 11 (10.4) | 17 (16.7) | 14 (13.6) | |
| Asian | 10 (2.3) | 4 (3.3) | 3 (2.8) | 3 (2.9) | ||
| Other | 39 (9) | 11 (9.2) | 13 (12.3) | 8 (7.8) | 7 (6.8) | |
| Payor | ||||||
| Government | 204 (47.3) | 63 (52.5) | 52 (49.1) | 43 (42.2) | 46 (44.7) | 0.667 |
| Private | 186 (43.2) | 45 (37.5) | 44 (41.5) | 51 (50) | 46 (44.7) | |
| Other | 41 (9.5) | 12 (10) | 10 (9.4) | 8 (7.8) | 11 (10.7) | |
| Any comorbidity | 314 (72.9) | 94 (78.3) | 92 (86.8) | 50 (49) | 78 (75.7) | <.001 |
| Hospital length of stay | 6 [3, 16] | 14 [6, 30] | 11 [5, 29] | 4 [2, 7] | 4 [3, 7] | <.001 |
| Reference standard sepsis | 130 (30.2) | 95 (79.2) | 19 (17.9) | 8 (7.8) | 8 (7.8) | <.001 |
| ICU admission | 300 (69.6) | 108 (90) | 59 (55.7) | 30 (29.4) | 103 (100) | <.001 |
| Mortality | 25 (5.8) | 18 (15) | 5 (4.7) | 0 (0.0) | 2 (1.9) | <.001 |
| Mechanical Ventilation | 167 (38.7) | 75 (62.5) | 55 (51.9) | 11 (10.8) | 26 (25.2) | <.001 |
| Vasoactive medications | 85 (19.7) | 71 (59.2) | 10 (9.4) | 1 (1) | 3 (2.9) | <.001 |