(A) qPCR analysis of liver gene expression in mice fed standard chow orWestern diet (WD) for 8 weeks (n = 5).
(B) Left, immunoblots of liver nuclear extracts; Right, quantitation of Baf60a protein levels after normalization to Lamin A/C.
(C) qPCR analysis of gene expression in livers from flox/flox and BaLKO mice (n = 5).
(D) Left, immunoblots of liver nuclear extracts; Right, quantitation of Baf60a protein levels after normalization to Lamin A/C.
(E-G) Plasma lipid levels (E), lipoprotein profile analysis (F), and concentrations of HDL-, LDL/VLDL-, and total-cholesterol (G) in flox/flox and BaLKO mice following 12 weeks of WD feeding (n = 5). Values are mean ± s.e.m.; *P < 0.05 by two-tailed Student's t-test.
See also Figure S1.