Table 1.
Correlation between disease parameters and MIBG scintigraphy or autonomic function tests.
| Disease duration (P value) |
H&Y (P value) |
LEDD (P value) |
|
|---|---|---|---|
| MIBG scintigraphy | |||
| Early H/M ratio | −0.10 (0.49) | −0.14 (0.32) | 0.07 (0.63) |
| Late H/M ratio | −0.06 (0.66) | −0.15 (0.31) | 0.11 (0.45) |
| Washout rate | 0.04 (0.81) | 0.19 (0.20) | −0.03 (0.85) |
| Autonomic function tests | |||
| HRV | |||
| LF component | −0.11 (0.44) | −0.08 (0.60) | −0.08 (0.57) |
| HF component | −0.26 (0.07) | −0.20 (0.17) | −0.17 (0.25) |
| LF/HF ratio | 0.16 (0.28) | 0.09 (0.55) | 0.11 (0.43) |
| CVR-R | −0.11 (0.49) | −0.09 (0.32) | −0.06 (0.68) |
| HUT test | |||
| SBP change | 0.03 (0.84) | −0.04 (0.78) | 0.00 (0.98) |
| DBP change | 0.18 (0.22) | 0.10 (0.50) | 0.08 (0.58) |
| HR change | 0.09 (0.52) | −0.12 (0.43) | 0.12 (0.39) |
Data are represented as Spearman correlation coefficients. H&Y, Hoehn and Yahr stage; LEDD, L-dopa equivalent daily dose; MIBG, 123I-metaiodobenzylguanidine myocardial scintigraphy; H/M ratio, heart to mediastinum ratio; HRV, heart rate variability; LF, low-frequency; HF, high-frequency; CVR-R, coefficient of variation of R-R intervals; HUT, head-up tilt; SBP, systolic blood pressure; DBP, diastolic blood pressure; HR, heart rate.