Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Synthesis of target analogs 15a-15b. Reagents and conditions: (a) Pd(PPh3)4, DME, K2CO3, reflux, 24h; (b) CH3NO2, NH4OAc, reflux, 4h; (c) LiBH4, TMSCI, THF, reflux; (d) HCOOEt, Et3N, DCM for 14a; (e) acetyl chloride, Et3N, DCM for 14b; (f) POCl3, MeCN, 50°C, 12h; (g) NaBH4, MeOH, 0°C, 4h; (h) HCNO, NaBH(OAc)3, DCM, rt, 24h.
