Table 2. Diagnostic criteria for hepatorenal syndrome.

• Presence of cirrhosis and ascites

• Diagnosis of AKI by ICA-AKI Criteria

• No improvement of serum creatinine after at least 48 h of diuretic withdrawal and volume expansion with albumin (recommended dose of 1 g/kg body weight per day to maximum of 100 g albumin/day

• Absence of shock

• No current or recent use of nephrotoxic drugs

• No macroscopic signs of structural kidney disease as defined as absence of proteinuria >500 mg/day, microhematuria (>50 RBCs/high power field), and/or abnormal renal ultrasound scanning.

AKI, acute kidney injury; RBCs, red blood cells.