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Nr2e1 silencing enhanced apoptosis of MIN6 cells. Comparison of cell apoptosis between control (MIN6-shc) and Nr2e1 silenced (MIN6-sh2 and MIN6-sh3) cells exposed to palmitate. MIN6-shc, MIN6-sh2, and MIN6-sh3 cells were cultured in complete medium with 0.5 mM palmitate overnight. Data represent means ± SD of three observations; ∗ P ≤ 0.05 (comparing silenced versus MIN6-shc cells exposed to palmitate).
