Table 3.
The distribution of genotypes, allele frequencies, and the analysis of the odds ratio (OR) for 242Pro/Arg polymorphism of PolB gene in patients with colorectal cancer (CRC) and the control group.
| Genotype/allele | Patients n = 303 | Controls n = 302∗ | OR (95% CI) | p |
|---|---|---|---|---|
| Pro/Pro | 147 | 121 | 1 (ref.) | — |
| Pro/Arg | 123 | 142 | 0.713 (0.507–1.003) | 0.052 |
| Arg/Arg | 33 | 39 | 0.697 (0.413–1.174) | 0.174 |
| Pro | 417 | 384 | 1 (ref.) | — |
| Arg | 189 | 220 | 0.772 (0.601–0.994) | 0.044 |
∗Genotype distribution in Hardy-Weinberg equilibrium; χ 2 = 0.791.