Table 4.
The distribution of genotypes, allele frequencies, and the analysis of the odds ratio (OR) for 780Arg/His polymorphism of LIG3 gene in patients with colorectal cancer (CRC) and the control group.
| Genotype/allele | Patients n = 310 | Controls n = 305∗ | OR (95% CI) | p |
|---|---|---|---|---|
| Arg/Arg | 101 | 121 | 1 (ref.) | — |
| Arg/His | 173 | 132 | 1.570 (1.109–2.224) | 0.011 |
| His/His | 36 | 52 | 0.829 (0.503–1.368) | 0.462 |
| Arg | 375 | 374 | 1 (ref.) | — |
| His | 245 | 236 | 1.035 (0.823–1.302) | 0.764 |
∗Genotype distribution in Hardy-Weinberg equilibrium; χ 2 = 0.125.