Table 5.
The distribution of genotypes and the analysis of the odds ratio (OR) for gene-gene interactions: 589Lys/Glu EXO1 and 242Pro/Arg PolB in patients with colorectal cancer (CRC) and the control group.
| Genotype | Patients n = 302 | Controls n = 302 | OR (95% CI) | p |
|---|---|---|---|---|
| Lys/Lys-Pro/Pro | 24 | 28 | 1 (ref.) | — |
| Lys/Lys-Pro/Arg | 20 | 26 | 0.897 (0.404–1.994) | 0.791 |
| Lys/Lys-Arg/Arg | 11 | 15 | 0.856 (0.331–2.212) | 0.752 |
| Lys/Glu-Pro/Pro | 99 | 51 | 2.265 (1.193–4.301) | 0.011 |
| Lys/Glu-Pro/Arg | 81 | 72 | 1.313 (0.698–2.467) | 0.396 |
| Lys/Glu-Arg/Arg | 19 | 23 | 0.964 (0.426–2.180) | 0.920 |
| Glu/Glu-Pro/Pro | 23 | 42 | 0.639 (0.303–1.346) | 0.238 |
| Glu/Glu-Pro/Arg | 22 | 44 | 0.583 (0.276–1.232) | 0.156 |
| Glu/Glu-Arg/Arg | 3 | 1 | — | — |