Table 6.
The distribution of genotypes and the analysis of the odds ratio (OR) for gene-gene interactions: 589Lys/Glu EXO1 and 780Arg/His LIG3 in patients with colorectal cancer (CRC) and the control group.
| Genotype | Patients n = 302 | Controls n = 302 | OR (95% CI) | p |
|---|---|---|---|---|
| Lys/Lys-Arg/Arg | 21 | 27 | 1 (ref.) | — |
| Lys/Lys-Arg/His | 31 | 27 | 1.476 (0.684–3.185) | 0.320 |
| Lys/Lys-His/His | 3 | 15 | — | — |
| Lys/Glu-Arg/Arg | 64 | 46 | 1.789 (0.902–3.547) | 0.094 |
| Lys/Glu-Arg/His | 118 | 77 | 1.970 (1.041–3.731) | 0.036 |
| Lys/Glu-His/His | 17 | 23 | 0.950 (0.407–2.218) | 0.920 |
| Glu/Glu-Arg/Arg | 15 | 48 | 0.402 (0.178–0.906) | 0.026 |
| Glu/Glu-Arg/His | 18 | 26 | 0.890 (0.389–2.038) | 0.777 |
| Glu/Glu-His/His | 15 | 13 | 1.484 (0.582–3.784) | 0.409 |