Table 7.
The distribution of genotypes and the analysis of the odds ratio (OR) for gene-gene interactions: 242Pro/Arg PolB and 780Arg/His LIG3 in patients with colorectal cancer (CRC) and the control group.
| Genotype | Patients n = 302 | Controls n = 302 | OR (95% CI) | p |
|---|---|---|---|---|
| Pro/Pro-Arg/Arg | 52 | 56 | 1 (ref.) | — |
| Pro/Pro-Arg/His | 82 | 41 | 2.154 (1.265–3.667) | 0.004 |
| Pro/Pro-His/His | 12 | 24 | 0.539 (0.245–1.185) | 0.121 |
| Pro/Arg-Arg/Arg | 38 | 48 | 0.853 (0.483–1.506) | 0.584 |
| Pro/Arg-Arg/His | 66 | 73 | 0.974 (0.589–1.611) | 0.920 |
| Pro/Arg-His/His | 19 | 21 | 0.974 (0.471–2.015) | 1.000 |
| Arg/Arg-Arg/Arg | 9 | 15 | 0.646 (0.261–1.603) | 0.343 |
| Arg/Arg-Arg/His | 20 | 17 | 1.267 (0.599–2.679) | 0.538 |
| Arg/Arg-His/His | 4 | 7 | — | — |