Table 4.

Factors associated with hepatocellular carcinoma development (n = 231)

Risk factor	Univariate analysis	Multivariate analysis	OR	95%CI
	P-value	P-value
Age (over 60 yr)	0.012	Not significant
HCC treatment history	< 0.001	< 0.001	15.27	4.98-59.51
AFP levels at 24 wk after IFN treatment ≥ 10 ng/mL	0.003	0.009	3.89	1.38-11.94
DCP levels at 24 wk after IFN treatment ≥ 40 mAU/mL	< 0.001	< 0.001	24.43	4.11-238.67

HCC: Hepatocellular carcinoma; AFP: Alpha-fetoprotein; IFN: Interferon; DCP: Des-gamma-carboxy prothrombin.