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. 2015 Nov 27;5(11):e008220. doi: 10.1136/bmjopen-2015-008220

Table 5.

Sensitivity analyses

Base case analysis*
Sensitivity analysis
Imputation and costs Total costs € SD Total costs € SD Mean difference CI†
Method of imputation, mean € 29 429.7 1977.41 28 524.4 1666.51 −905 (−5963 to 3999)
Rehabilitation treatment day, mean € 29 363.3 1864.74 2689.3 1674.97 −3274 (−8053 to 1840)
Production losses, mean € 29 356.0 1858.82 31 521.3 2099.90 2165 (−3065 to 7896)
Perspective, mean € 29 490.6 1929.14 18 047.6 1335.40 −11 443 (−15 978 to −6796)
Quality of life Utility SD Utility SD Mean difference p Value
Average utility score 2 months poststroke 0.73 0.24 0.67 0.28 −0.049 0.000
Average utility score 6 months poststroke 0.74 0.25 0.69 0.29 −0.049 0.000
Average utility score 12 months poststroke 0.74 0.24 0.70 0.32 −0.037 0.000

*Base case analysis uses the original method of imputation, values a rehabilitation day as a hospital treatment day, calculates production losses by means of the friction cost method, uses the societal perspective to calculate total costs and calculates utilities with a Dutch tariff. Sensitivity analyses uses mean imputation to calculate total costs, values a rehabilitation treatment day as a rehabilitation contact, calculates production losses with the human capital approach, estimates of total healthcare costs and utilities are calculated with a UK tariff.

†If CI includes 0, no significant difference is found.

‡Significant differences estimated by means of the Wilcoxon signed-rank test; Critical p=0.005.