Table 5.
Base case analysis* |
Sensitivity analysis |
|||||
---|---|---|---|---|---|---|
Imputation and costs | Total costs € | SD | Total costs € | SD | Mean difference | CI† |
Method of imputation, mean € | 29 429.7 | 1977.41 | 28 524.4 | 1666.51 | −905 | (−5963 to 3999) |
Rehabilitation treatment day, mean € | 29 363.3 | 1864.74 | 2689.3 | 1674.97 | −3274 | (−8053 to 1840) |
Production losses, mean € | 29 356.0 | 1858.82 | 31 521.3 | 2099.90 | 2165 | (−3065 to 7896) |
Perspective, mean € | 29 490.6 | 1929.14 | 18 047.6 | 1335.40 | −11 443 | (−15 978 to −6796) |
Quality of life | Utility | SD | Utility | SD | Mean difference | p Value‡ |
Average utility score 2 months poststroke | 0.73 | 0.24 | 0.67 | 0.28 | −0.049 | 0.000 |
Average utility score 6 months poststroke | 0.74 | 0.25 | 0.69 | 0.29 | −0.049 | 0.000 |
Average utility score 12 months poststroke | 0.74 | 0.24 | 0.70 | 0.32 | −0.037 | 0.000 |
*Base case analysis uses the original method of imputation, values a rehabilitation day as a hospital treatment day, calculates production losses by means of the friction cost method, uses the societal perspective to calculate total costs and calculates utilities with a Dutch tariff. Sensitivity analyses uses mean imputation to calculate total costs, values a rehabilitation treatment day as a rehabilitation contact, calculates production losses with the human capital approach, estimates of total healthcare costs and utilities are calculated with a UK tariff.
†If CI includes 0, no significant difference is found.
‡Significant differences estimated by means of the Wilcoxon signed-rank test; Critical p=0.005.