Table 1. Viability of P. aeruginosa PAO1 persister cells isolated from stationary cultures after treatment with GM-CSF and/or selected antibiotics.
| Antibiotic | Change in viability (compared to antibiotic alone) |
|||
|---|---|---|---|---|
| GM-CSF Concentration | ||||
| 0 pM | 0.17 pM | 1.7 pM | 17 pM | |
| No antibiotic | − | NC | NC | NC |
| Ciprofloxacin (5 μg/mL) | NC | −61.5 ± 14.5% ** | −53.8 ± 16.1%** | −74.0 ± 2.9%*** |
| Tobramycin (5 μg/mL) | NC | −77.1 ± 2.0%*** | −82.7 ± 2.3%*** | −86.5 ± 1.7%*** |
**p < 0.01, ***p < 0.001, one-way ANOVA followed by Tukey test. NC: No significant change.