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. 2015 Nov 30;5:17447. doi: 10.1038/srep17447

Figure 4. PREX2 is closely involved in processes surrounding TARP mediated Chlamydial entry.

Figure 4

Downstream signalling via RAC leads to changes in cell cycle control and actin skeleton rearrangements that facilitate infection. PREX2 can indirectly mediate downstream changes to cell cycle control and glucose homeostasis via RAC and Akt/p53.