Table 1. Index SNPs (Pemmax ≤ 5 × 10−6, at least one supporting SNP in LD with R2 > 0.6) for candidate associated regions.
RSID | CHR | POSITION Assembly 3GRCh37.p13 | ALLELES (effect allele bold) | Freq EA | Type | P | OR*,** | Within gene |
---|---|---|---|---|---|---|---|---|
rs116828186 | 3 | 18854524 | A,G | 0.027 | Genotyped | 1.37E-06 | 0.824 | — |
rs28731189 | 5 | 11212170 | C,T | 0.011 | Imputed | 1.42E-06 | 0.736 | CTNND2 |
rs74291850 | 5 | 29577370 | T,C | 0.022 | Imputed | 4.63E-07 | 1.291 | — |
rs187984259 | 5 | 73681906 | T,C | 0.016 | Imputed | 1.43E-06 | 0.758 | — |
rs80317841 | 6 | 132398394 | G,C | 0.84 | Genotyped | 1.97E-06 | 1.092 | — |
rs116141145 | 7 | 97249265 | A,G | 0.037 | Imputed | 1.24E-06 | 1.190 | — |
rs111513399 | 8 | 69036056 | A,G | 0.113 | Imputed | 5.38E-07 | 1.114 | PREX2 |
rs11258313 | 10 | 13339766 | G,A | 0.233 | Imputed | 1.35E-06 | 1.101 | PHYH |
rs12774519 | 10 | 18925493 | C,G | 0.191 | Imputed | 2.06E-06 | 1.086 | NSUN6 |
rs9895748 | 17 | 5053598 | T,A | 0.068 | Imputed | 1.72E-06 | 0.872 | USP6 |
rs62079945 | 18 | 10247566 | A,C | 0.048 | Imputed | 1.22E-06 | 0.842 | — |
rs6033064 | 20 | 1175527 | T,C | 0.803 | Imputed | 9.94E-07 | 0.909 | — |
*Expected frequency of the effect allele.
**The OR indicates the estimated allele frequency odds ratio for the effect allele. Values less than one indicate that the effect allele is less common in cases than controls and vice versa.