Table 4. Gene Ontology terms associated with pathways of significance in PODA and ALIGATOR.
GO Terms: Biological Process | #genes in list | P value for GO term* | UA value for cluster** |
---|---|---|---|
Microtubule-based Process | 443 | 2.3 × 10−21 | 100 |
G-protein coupled Receptor protein signalling pathway | 353 | 1.3 × 10−116 | 91 |
Cellular response to hormone stimulus | 53 | 2.5 × 10−24 | 100 |
Cell surface receptor linked signal transduction | 147 | 2.4 × 10−24 | 97 |
Cell Cycle | 1380 | 4.8 × 10−189 | 100 |
Regulation of T cell activation | 82 | 2.1 × 10−15 | 100 |
Sodium Ion Transport | 175 | 2.1 × 10−61 | 100 |
Phosphorous metabolic process | 36 | 4.3 × 10−2 | 98 |
Regulation of phosphorylation | 131 | 2.6 × 10−13 | 97 |
*Modified Fisher exact P, EASE SCORE.
**Unbiased Alpha.