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. 2015 Nov 16;7(11):4773–4796. doi: 10.3390/toxins7114773

Table 1.

Effect of chronic enteral deoxynivalenol (DON) exposure and pre- or post-hepatic E. coli lipopolysaccharide (LPS) infusion on arterial, venous or portal red hemogram in pigs.

Parameter Overall Mean PSEM p-Values
Group Catheter Time G × C × T
RBC (×10 6 cells/µL) 5.57 0.24 0.306 0.299 <0.001 0.467
Hct (%) 30.44 1.40 0.629 0.006 <0.001 0.415
Hgb (g/dL) 10.82 0.49 0.618 0.073 T <0.001 0.279
MCV (fL) 54.78 1.26 0.632 <0.001 0.981 0.036
MCH (g/dL) 19.48 0.52 0.602 0.144 <0.001 0.080 T
MCHC (g/dL) 35.56 0.52 0.554 0.001 <0.001 0.429

Notes: RBC = red blood cells (reference: 5.5–8.5 × 10 6 cells/µL 1); Hct = hematocrit (reference: 33%–45% 1); Hgb = hemoglobin (reference: 10.16–14.03 g/dL 1); MCV = mean corpuscular volume (reference: 50–65 fL 1); MCH = mean corpuscular hemoglobin (reference: 17–21 g/dL 1); MCHC = mean corpuscular hemoglobin concentration (reference: 30–35 g/dL 1); 1 = [26]; references in venous blood; T = trend (p ≤ 0.10); PSEM = pooled standard error of means. Barrows were either fed a DON contaminated ration (DON; 4.59 mg/kg feed) or control feed (CON) during 29 days. Infusion groups were divided as follows: pre-hepatic LPS infusion (CON_CONjugular-LPSportal, n = 7 and DON_CONjugular-LPSportal, n = 6), post-hepatic LPS infusion (CON_LPSjugular-CONportal, n = 8 and DON_LPSjugular-CONportal, n = 6), and control infusion (CON_CONjugular-CONportal, n = 7 and DON_CONjugular-CONportal, n = 7). Infusion from time 0 until 60 min with 7.5 µg LPS/kg BW in 0.9% saline. Feed was offered during 15 min prior to infusion start. Blood samples were collected at times: −30, 15, 30, 45, 60, 75, 90, 120, 150, 180 min.