Table 2.
Effect of chronic enteral deoxynivalenol (DON) exposure and pre- or post-hepatic E. coli lipopolysaccharide (LPS) infusion on arterial, venous or portal blood electrolytes in pigs.
| Parameter | Overall Mean | PSEM | p-Values | |||
|---|---|---|---|---|---|---|
| Group | Catheter | Time | G × C × T | |||
| Na+ (mmol/L) | 142.90 | 1.15 | 0.449 | <0.001 | <0.001 | 0.629 |
| Cl− (mmol/L) | 105.45 | 1.16 | 0.702 | <0.001 | <0.001 | 0.67 |
| K+ (mmol/L) | 4.28 | 0.16 | 0.585 | <0.001 | <0.001 | <0.001 |
| iCa2+ (mmol/L) | 1.37 | 0.03 | 0.985 | <0.001 | <0.001 | 0.006 |
Notes: Na+ = sodium (reference: 140–160 mmol/L1); Cl− = chloride (reference: 102–106 mmol/L1); K+ = potassium (reference: 4.0–5.0 mmol/L 1); iCa2+ = calcium iones (reference: 0.87–1.45 mmol/L 2); 1 = [26]; 2 = [27]; references in venous blood; T = trend (p ≤ 0.10); PSEM = pooled standard error of Means. Barrows were either fed a DON contaminated ration (DON; 4.59 mg/kg feed) or control feed (CON) during 29 days. Infusion groups were divided as follows: pre-hepatic LPS infusion (CON_CONjugular-LPSportal, n = 7 and DON_CONjugular-LPSportal, n = 6), post-hepatic LPS infusion (CON_LPSjugular-CONportal, n = 8 and DON_LPSjugular-CONportal, n = 6), and control infusion (CON_CONjugular-CONportal, n = 7 and DON_CONjugular-CONportal, n = 7). Infusion from time 0 until 60 min with 7.5 µg LPS/kg BW in 0.9% saline. Feed was offered during 15 min prior to infusion start. Blood samples were collected at times: −30, 15, 30, 45, 60, 75, 90, 120, 150, 180 min.