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. 2015 Oct 30;7(11):8960–8976. doi: 10.3390/nu7115444

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Phenotype of intraepithelial lymphocytes in the duodenum from celiac patients. Phenotype of IELs in untreated Celiac Disease (uCD), Gluten Free Diet-CD patients (GFD-CD), inflamed non-CD controls (I-controls) and non-inflamed non-CD controls (C-controls), analyzed by flow cytometry: Percentage of total IELs (CD103⁺CD45⁺) referred to the total of epithelial cells (A). Percentage of non-T cells (CD103⁺CD45⁺CD3⁻) (B), Tγδ cells (CD103⁺CD45⁺CD3⁺TCRγδ⁺) (C) and Tαβ cells (CD103⁺CD45⁺CD3⁺TCRγδ⁻) (D) referred to the total of IELs. Horizontal bar are median values. Statistically significant differences are shown (two tailed Mann Whitney U test; p < 0.05). Representative flow cytometry analysis data of IEL subpopulations (Tγδ, Tαβ and non-T cells) in uCD, GFD-CD, I-controls and C-controls (E).

Phenotype of intraepithelial lymphocytes in the duodenum from celiac patients. Phenotype of IELs in untreated Celiac Disease (uCD), Gluten Free Diet-CD patients (GFD-CD), inflamed non-CD controls (I-controls) and non-inflamed non-CD controls (C-controls), analyzed by flow cytometry: Percentage of total IELs (CD103⁺CD45⁺) referred to the total of epithelial cells (A). Percentage of non-T cells (CD103⁺CD45⁺CD3⁻) (B), Tγδ cells (CD103⁺CD45⁺CD3⁺TCRγδ⁺) (C) and Tαβ cells (CD103⁺CD45⁺CD3⁺TCRγδ⁻) (D) referred to the total of IELs. Horizontal bar are median values. Statistically significant differences are shown (two tailed Mann Whitney U test; p < 0.05). Representative flow cytometry analysis data of IEL subpopulations (Tγδ, Tαβ and non-T cells) in uCD, GFD-CD, I-controls and C-controls (E).